Which symptom is NOT typically associated with opioid withdrawal?

Opioid withdrawal symptoms reflect the physiological adaptations that occur with long-term opioid use when the substance is discontinued. Symptoms typically include muscle spasms, diarrhea, and insomnia, all of which are a result of the body's rebound effects as it readjusts to functioning without the opioid.

Muscle spasms occur due to the lack of opioid-mediated regulation of pain and muscle tone following cessation. Diarrhea often results from increased gastrointestinal activity and the loss of the constipating effect that opioids have when taken regularly. Insomnia can arise as the body experiences heightened levels of arousal and anxiety once the sedative effect of opioids is removed.

Cough, while it can occur due to various causes, is not a classical symptom of opioid withdrawal. It does not fit the withdrawal syndrome's primary profile and is more commonly associated with respiratory issues or a side effect of other substances. Therefore, it stands out as not typically being a symptom of opioid withdrawal.