Which of the following antipsychotics is classified as having low potency?

Prepare for the Advanced Pharmacology – Psychopharmacology exam. Study with interactive quizzes, flashcards, and detailed explanations for each question. Enhance your understanding and ace your test!

The correct choice of antipsychotics classified as having low potency is thioridazine. This drug belongs to the older class of antipsychotics, known as typical antipsychotics, which are grouped based on their potency.

Low-potency antipsychotics are generally characterized by a higher sedation level and a lower capacity to produce extrapyramidal symptoms at therapeutic doses compared to high-potency antipsychotics. Thioridazine, along with other low-potency agents, exhibits a significant sedative effect and can cause adverse effects unique to this potency category.

Mesoridazine is also a low-potency antipsychotic; however, it is often considered less commonly used and is secondary to thioridazine in classification within the same category. Haloperidol and fluphenazine, on the other hand, are high-potency antipsychotics and are known for their lower sedation levels but a greater risk of extrapyramidal symptoms, which is a key distinction among these medications in their therapeutic effects and side effect profiles.

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