What unique indication is duloxetine (Cymbalta) effective for at higher doses?

Duloxetine (Cymbalta) is uniquely indicated for the management of somatic symptoms of depression, particularly at higher doses. This medication belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs) and is effective in addressing both emotional symptoms of depression and associated physical symptoms, such as pain, fatigue, and other somatic complaints.

When used at higher doses, duloxetine can provide significant relief from these physical manifestations that often accompany major depressive disorder. Research supports its efficacy in treating not just mood but also the somatic aspects of depression, making it a valuable option in clinical practice.

The other indications listed, while they may have some association with the use of duloxetine, do not specifically highlight the unique role duloxetine plays in treating somatic symptoms of depression at higher doses.