What is the recommended condition for maximum absorption of Lurasidone (Latuda)?

Lurasidone (Latuda) is an atypical antipsychotic medication that has specific requirements for optimal absorption. For maximum bioavailability, Lurasidone should be taken with food, specifically with a meal containing at least 350 calories. This requirement enhances the drug's absorption due to the pharmacokinetic properties of the formulation, allowing for better therapeutic effectiveness.

Taking Lurasidone with food increases the serum concentration, ensuring that the medication can exert its intended effects more efficiently. This is particularly important in the context of managing psychiatric disorders, where consistent and effective medication levels are crucial for symptom control.

While other options suggest different conditions for administration, they do not meet the criteria established for optimal absorption of Lurasidone. For example, taking it on an empty stomach would lead to decreased absorption, and high-fat meals may alter the pharmacokinetics unfavorably. Furthermore, the timing of administration, such as taking it before bedtime, does not address the critical factor of food intake related to absorption. Therefore, the recommendation is to take Lurasidone with food, specifically ensuring that the meal provides adequate calories for optimal effectiveness.