What is the function of Naltrexone in relation to opioid use?

Naltrexone serves as an opioid antagonist, which means its primary function is to block mu-opioid receptors in the brain. This action effectively prevents opioids from exerting their effects, such as pain relief and euphoria, which are typically associated with opioid use. By occupying these receptors, Naltrexone reduces the reinforcing effects of opioids, helping to decrease cravings and the risk of relapse in individuals with opioid dependence.

This mechanism is therapeutic in managing opioid abuse disorders, as it allows individuals to avoid the euphoric effects of opioids if they were to use them while on Naltrexone. The other choices assert actions that are contrary to Naltrexone’s pharmacological profile, as it does not increase cravings, promote consumption, or induce withdrawal symptoms, though some individuals may experience withdrawal if they have opioids in their system when they begin taking Naltrexone.