What is one of the common treatment modalities for Neuroleptic Malignant Syndrome (NMS)?

Hydration is a critical treatment modality for Neuroleptic Malignant Syndrome (NMS) due to the risk of dehydration and its associated complications that can arise from the syndrome. NMS is characterized by severe muscle rigidity, hyperthermia, autonomic instability, and altered mental status. The rigidity can lead to increased muscle metabolism, resulting in elevated creatine kinase levels and potential renal failure. Administering fluids helps maintain renal perfusion, mitigate the effects of muscle breakdown, and support overall metabolic function. Additionally, hydration can help lower body temperature, which is often dangerously elevated in cases of NMS, contributing to further complications.

Other treatment strategies may include the use of medications such as dantrolene or bromocriptine to directly address the symptoms of NMS, but ensuring proper hydration is a fundamental first step in managing this life-threatening condition.