In treating binge eating disorder, which medication is used?

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Lisdexamfetamine is an effective choice for the treatment of binge eating disorder due to its mechanism of action as a stimulant. It works by increasing the release of neurotransmitters such as norepinephrine and dopamine, which can help regulate mood, decrease impulsivity, and curb the frequency of binge eating episodes. Clinical studies have shown that lisdexamfetamine can significantly reduce binge eating frequency and improve associated symptoms.

In contrast, high-dose fluoxetine has been used, but its efficacy is less established for binge eating disorder compared to lisdexamfetamine. While olanzapine is an antipsychotic that might be considered in certain cases, it is not typically indicated for binge eating disorder and may lead to weight gain, which can exacerbate the condition. Bupropion is primarily used for depression and smoking cessation; it is contraindicated in eating disorders due to the increased risk of seizures. Thus, lisdexamfetamine stands out as the most appropriate medication for this disorder.

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