According to the content, which factor is considered an extreme caution when prescribing antipsychotics?

Clients with metabolic disorders require extreme caution when prescribing antipsychotics due to the significant risk of exacerbating these conditions. Antipsychotics can lead to metabolic changes, including weight gain, dyslipidemia, and insulin resistance, which can further complicate existing metabolic disorders. This class of medications is known to influence metabolic parameters, making it crucial to assess and closely monitor clients with such pre-existing conditions.

In contrast, while advanced age and cognitive impairments also warrant careful consideration, the direct association between antipsychotic side effects and metabolic disorders makes this factor particularly critical. Aging clients may be at increased risk for side effects, but metabolic disorders can predispose individuals to serious cardiovascular and endocrine complications, directly influencing their overall health outcomes. History of anxiety disorders may involve considerations for co-occurring medications or therapeutic approaches, but they do not pose the same immediate metabolic risks associated with antipsychotic use.